Neat News 3581 (added 2026-04-29)

Molecular switch and Alzheimer's

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Studying the brains of dead older adults it has been found that around 20 to 30 percent of them have had asymptomatic Alzheimer's disease with a buildup of misfolded amyloid-beta and tau proteins, but with no prior signs of cognitive decline. In experiments with mice, it has been discovered that the buildup on its own is not sufficient for cognitive decline, but also a molecular switch needs to be flipped. More research is needed to find a potential new treatment against the disease.

related: #Alzheimer #molecular_switch #cognitive_decline